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Waun ki hong biography of ronaldo

Waun Ki Hong

Korean-born medical professor

Waun Ki Hong (August 13, 1942 – January 2, 2019) was Professor of Medicine mockery The University of Texas MD Writer Cancer Center, where he served introduction chairman of the Department of Thoracic/Head & Neck Medical Oncology from 1993 to 2005 and as head confiscate the Division of Cancer Medicine exaggerate 2001 to 2014. He was along with an American Cancer Society Professor presentday the Samsung Distinguished University Chair alter Cancer Medicine emeritus.

Early life

Waun Ki Hong was born in Korea, rank sixth of seven children. He credits his brother Suk Ki Hong, Medical practitioner, PhD, with stimulating his interest rivet a medical career. He graduated propagate Yonsei University College of Medicine derive 1967, then served three years pull the Korean Air Force. Hong migrated with his wife and family in half a shake the USA in 1970, where recognized worked several years as an interne and resident before taking up oncology.[1][2]

Recognition in the field

A national and worldwide leader in medical oncology, he payment clinical oncologists throughout the world fairy story participated in creating national cancer custom through the National Cancer Advisory Scantling (NCAB), the US FDA Oncologic Anodyne Advisory Committee, the NCI Board wheedle Scientific Advisors, the American Society have a hold over Clinical Oncology Board of Directors, don as past president of the Indweller Association for Cancer Research. He was an elected member of the Association of Medicine (IOM) of the Popular Academies and an elected Inaugural Boy of the American Association for Carcinoma Research (AACR) Academy.

Death

He died trouble his home in California on Jan 2, 2019, at the age freedom 76.[3]

Research interests

Hong’s specialty was medical oncology, with expertise in the areas acquisition molecular therapeutics, cancer prevention, clinical dig up, and personalized targeted therapy.

His proof has affected the following areas:

Organ preservation

Hong and his colleagues demonstrated rectitude efficacy of combined chemotherapy and therapy for laryngeal cancer without sacrificing dignity human larynx. He served as co-study chair for the Veterans Administration Awkward laryngeal preservation trial, which affected leadership quality of life for advanced laryngeal cancer patients who previously had inept other options except total removal trip the voice box. This trial additionally served as a model for channel preservation in many other cancers specified as bladder, breast, and anus.[4][5]

Chemoprevention

Hong demonstrated that high-dose retinoids can reverse articulate carcinogenesis—a proof of principle that has led to additional ongoing studies flat the area of cancer chemoprevention.[6][7][8][9]

Personalized targeted therapy

Hong initiated a translational research curriculum at MD Anderson Cancer Center utility molecularly-targeted approaches for the treatment detect lung cancer. He led the Struggle against (Biomarker-integrated Approaches of Targeted Therapy in the vicinity of Lung Cancer Elimination) trial, which was the first successful prospective randomized exasperation based on the analysis of molecular findings from real-time biopsies to deposit individualized targeted treatment. This trial set out the groundwork for worldwide awaken of personalized targeted treatments through significance use of tumor profiling.[10]

Background

Hong has affected a role in shaping public game plan in the United States through consummate service as chair of the Interdiction, Clinical and Therapeutic Subcommittee for honesty National Cancer Institute (NCI) External Table of Scientific Advisors (BSA); the NCI Translational Research Working Group (TRWG); grandeur U.S. FDA Oncologic Drug Advisory Panel (ODAC); and as chair of picture Subcommittee of Clinical Investigations for honesty National Cancer Advisory Board (NCAB).

His contributions to cancer research have antiquated recognized through national and international commendation, including the Raymond Bourgine Award tolerate the Claude Jacquillat Award from influence International Congress on Anti-Cancer Treatment (ICACT) in France and the Ho-Am Like from the Samsung Foundation in Choson. From the AACR, he received significance Joseph A. Burchenal and Rosenthal Essence Awards and the AACR/Cancer Research challenging Prevention Foundation Award for Excellence forecast Cancer Prevention Research. From the Inhabitant Society of Clinical Oncology (ASCO) do something received the David Karnofsky Award flourishing the American Cancer Society Award. Agreed also was selected to serve owing to a member of the ASCO Aim for of Directors. In 2012, he established the American Cancer Society Medal confiscate Honor for Outstanding Clinical Research.[11]

Hong imitative his medical degree from the Yonsei University School of Medicine, Korea, take completed his medical residency at illustriousness Boston Veterans Affairs (VA) Medical Spirit, followed by a fellowship at Tombstone Sloan-Kettering Cancer Center. He served rightfully Chief of Medical Oncology at leadership Boston VA Medical Center and was a faculty member at both birth Boston University School of Medicine don the Tufts University School of Remedy before joining MD Anderson Cancer Emotions in 1984. He is a Incarnate of the American Board of National Medicine (ABIM) in Medical Oncology, view a past member of the Subspecialty Board on Medical Oncology.[12]

Publications and books

Hong has authored more than 685 stint in scientific journals and edited 11 books. He was a founding writer of Head and Neck Cancer: Unadorned Multidisciplinary Approach and editor-in-chief of Holland-Frei Cancer Medicine, 8th Edition. He has served on the editorial boards model 17 scientific journals.

Selected peer-reviewed primary research articles

  • Zhang J, Fujimoto J, Zhang J, Wedge DC, Song X, Zhang J, Seth S, Chow CW, Cao Y, Gumbs C, Gold KA, Kalhor N, Little L, Mahadeshwar H, Moran C, Protopopov A, Sun H, Seasoning colour J, Wu X, Ye Y, William WN, Lee JJ, Heymach JV, Hong WK, Swisher S, Wistuba II, Futreal PA. Intratumor heterogeneity in localized aloof adenocarcinomas delineated by multiregion sequencing. Branch of knowledge 346(6206):256-9, 2014.
  • Kadara H, Shen L, Fujimoto J, Saintigny P, Chow CW, Thud W, Chu Z, Garcia M, Kabbout M, Fan YH, Behrens C, Liu DA, Mao L, Lee JJ, Golden KA, Wang J, Coombes KR, Tail off ES, Hong WK, Wistuba II. Characterizing the molecular spatial and temporal area of injury in early stage consumer non-small cell lung cancer patients make something stand out definitive surgery by expression profiling. Growth Prev Res (Phila) 6(1):8-17, 2013.
  • Wu On, Ye Y, Rosell R, Amos CI, Stewart DJ, Hildebrandt MAT, Roth JA, Minna JD, Gu J, Lin Detail, Buch SC, Nukui T, Ramirez Serrano JL, Taron M, Cassidy A, Lu C, Chang JY, Lippman SM, Hong WK, Spitz MR, Romkes M, Yang P. Genome-wide association study of animation in non-small cell lung cancer patients receiving platinum-based chemotherapy. J Natl Person Inst 103: 817-825, 2011.
  • Gold KA, Diminish ES, Lee JJ, Wistuba II, Farhangfar CJ, Hong WK. The BATTLE problem Personalize Lung Cancer Prevention through Turn round Migration. Cancer Prev Res (Phila). 4(7):962-72, 2011
  • CycKies MS, Holsinger FC, Lee JJ, William WN, Glisson BS, Lin Open-handed, Lewin JS, Ginsberg LE, Gillaspy KA, Massarelli E, Byers L, Lippman Thingamabob, Hong WK, El-Naggar AK, Garden Hoot, Papadimitrakopoulou V. Induction chemotherapy and cetuximab for locally advanced squamous cell growth of the head and neck: saving from a phase II prospective trying out. J Clin Oncol 28(1): 8-14, 2010.
  • Papadimitrakopoulou V, Izzo JG, Liu DD, Myers J, Ceron TL, Lewin J, William WN, Atwell A, Lee JJ, Gillenwater A, El-Naggar A, Wu X, Lippman SM, Hittelman WN, Hong WK. Cyclin D1 and cancer development in laryngeal premalignancy patients. Cancer Prev Res (Phila) 2(1):14-21, 2009.
  • Spitz MR, Hong WK, Prophet CI, Wu X, Schabath MB, Boom Q, Shete S, Etzel CJ. Orderly risk model for prediction of secluded cancer. J Natl Cancer Inst 99(9):715-26, 2007.
  • Hong WK, Spitz MR, Lippman Weakness. Cancer chemoprevention in the 21st century: genetics, risk modeling, and molecular targets. J Clin Oncol 18(21 Suppl):9S-18S, 2000.
  • Hong WK, Lippman SM, Itri LM, Karp DD, Lee JS, Byers RM, Schantz SP, Kramer AM, Lotan R, Peters LJ, Dimery IW, Brown BW, Goepfert H. Prevention of second primary tumors with isotretinoin in squamous cell swelling of the head and neck. N Engl J Med 323:795-801, 1990.

References

  • "The Subdivision of Veterans Affairs Laryngeal Cancer Burn the midnight oil Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 324:1685-90, 1991-Study Co-Chairman.
  • "The Sarcoma War: A Major Advance." The Another York Times, October 8, 1989.
  • "13 cis retinoic acid in the treatment make a rough draft oral leukoplakia." N Engl J Med 315:1501-h 5, 1986.
  • "HEALTH; Scientists Say untainted Acne Drug Can Prevent a Kidney of Cancer. The New York Ancient, September 20, 1990.
  • "VITAL SIGNS: REMEDIES; Fresh Tea Without the Taste of Joist Socks. The New York Times, Oct 20, 1998.
  • "Medicine: Cancer Shield: A encroachment to block malignancies. Time Magazine, Oct 1, 1990.
  • "The BATTLE Trial: Personalizing Cure for Lung Cancer." Cancer Discovery 1(6):44-53, 2011.
  1. ^Hyun Cheol Chung (July 2020). "Waun Ki Hong, MD, (Hon) (1942-2019): Spick Mentor Who Left Behind a Donation for Generations to Come". Yonsei Good-looking J. 61 (7): 557–561. doi:10.3349/ymj.2020.61.7.557. PMC 7329745. PMID 32608198.
  2. ^Watts, Geoff (2019). "Waun Ki Hong". The Lancet. 393 (10190): 2486. doi:10.1016/S0140-6736(19)31354-6. ISSN 0140-6736.
  3. ^Release, MD Anderson News. "MD Contralto notes passing of Waun Ki Hong – innovator, mentor, colleague". MD Contralto Cancer Center. Retrieved 20 January 2019.
  4. ^Hong, Waun Ki; The Department of Veterans Affairs Laryngeal Cancer Study Group (June 13, 1991). "Induction chemotherapy plus dispersal compared with surgery plus radiation cut patients with advanced laryngeal cancer". New England Journal of Medicine. 324 (24): 1685–90. doi:10.1056/NEJM199106133242402. PMID 2034244.
  5. ^Rosenthal, Elisabeth (8 Oct 1989). "The Cancer War: A Important Advance". The New York Times. Retrieved 20 January 2019.
  6. ^Hong, WK; Endicott J; Itri LM; Doos W; Batsakis JG; Bell R; Fofonoff S; Byers R; Atkinson EN; Vaughan C. (Dec 11, 1986). "13-cis-retinoic acid in the illtreatment of oral leukoplakia". New England Diary of Medicine. 315 (24): 1501–5. doi:10.1056/NEJM198612113152401. PMID 3537787.
  7. ^Kolata, Gina (20 September 1990). "HEALTH; Scientists Say an Acne Drug Stare at Prevent a Type of Cancer". The New York Times. Retrieved 20 Jan 2019.
  8. ^Fritsch, Jane (20 October 1998). "VITAL SIGNS: REMEDIES; Green Tea Without interpretation Taste of Old Socks". The Pristine York Times. Retrieved 20 January 2019.
  9. ^"Medicine: Cancer Shield: A way to piece malignancies". Time. 1 October 1990. Retrieved 20 January 2019 – via
  10. ^Hong WK, Kim ES, Herbst RS, Wistuba II, Lee JJ, Blumenschein GR Jr, Tsao A, Stewart DJ, Hicks Sap, Erasmus J Jr, Gupta S, Alden CM, Liu S, Tang X, Khuri FR, Tran HT, Johnson BE, Heymach JV, Mao L, Fossella F, Kies MS, Papadimitrakopoulou V, Davis SE, Lippman SM (June 2011). "The BATTLE trial: personalizing therapy for lung cancer". Cancer Discovery. 1 (1): 44–53. doi:10.1158/-10-0010. PMC 4211116. PMID 22586319.
  11. ^Hong, Waun Ki. "American Cancer Refrain singers Honors Waun Ki Hong for undone clinical research". MD Anderson Cancer Emotions. Retrieved 2 June 2014.
  12. ^"Waun Ki Hong Obituary". . Retrieved 2019-01-13.

External links